Why is GoutClear™ So Effective in Uric Acid Reduction?
GoutClear is a breakthrough solution that effectively combines extensively researched ingredients known to minimize uric acid accumulation in the joints and relieve inflammation. Each ingredient in GoutClear was handpicked based on clinical data. GoutClear can help to minimize uric acid accumulation in the joints, decrease water retention, promote healthy kidney function, and relieve joint inflammation.
GoutClear's key ingredients have been scientifically recognized for their restorative health benefits. The proprietary blend of vitamins, minerals, and herbs is what makes GoutClear so effective. The ingredients in GoutClear have been hand selected for their effectiveness and regenerative properties!
Adding GoutClear to your daily routine can help your body maintain optimal uric acid levels without any unwanted side effects. GoutClear's proprietary formulation can be taken daily without the risk of toxic substance build up. Just 2 capsules a day help to restore your health.
GoutClear's - Proprietary Blend of Ingredients:
Tart Cherry Extract: Improves the body's ability to reduce inflammation and deal with oxidative stress such as might occur with exercise or a joint inflammation. Tart Cherry helps reduce uric acid levels possibly because its anthocyanidins inhibit xanthine oxidase, an enzyme involved in the production of uric acid. Thus the body makes less uric acid. You can also order this ingredient in an extract for increased strength.
- Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial. Kuehl KS, Perrier ET, Elliot DL, Chesnutt JC. J Int Soc Sports Nutr. 2010 May 7;7:17.
- Tart cherry juice decreases oxidative stress in healthy older men and women. Traustadóttir T, Davies SS, Stock AA, Su Y, Heward CB, Roberts LJ 2nd, Harman SM. J Nutr. 2009 Oct;139(10):1896-900.
Artichoke The flower of the artichoke has been used as a food and medicinal agent for centuries. Basic science studies demonstrate that artichoke inhibits the enzyme (XO) responsible for uric acid production. Uric acid buildup leads to the symptoms of gout. Artichoke also has the added benefit of lowering cholesterol.
- Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application. Sarawek S, Feistel B, Pischel I, Butterweck V. Planta Med. 2008 Feb;74(3):221-7.
- Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 8th ed. 2007 Saunders. Chapter 47.
Garlic Garlic is widely used for food flavoring and there are many other reported uses. Evidence suggests a mild improvement in gout symptoms. The main beneficial effects are for heart health and lowering cholesterol. There is a mild lowering of LDL cholesterol (often referred to as "bad cholesterol") and triglycerides.
- Ferri: Ferri's Clinical Advisor 2011, 1st ed. Appendix Ib.
Yucca Herb Stock Leaf The Yucca leaf has been traditionally used for rheumatic diseases such as arthritis. Recent evidence supports this use, as constituents of the yucca plant have been found to be anti-inflammatory. Other substances in the yucca plant have been shown to have antioxidant activity as well. The yucca plant also contains resveretrol, a potent antioxidant and a recent review of the literature indicated that yucca holds promise in the treatment of arthritis and other inflammatory conditions.
- Wenzig EM, Oleszek W, Stochmal A, Kunert O, Bauer R. Influence of phenolic constituents from Yucca schidigera bark on arachidonate metabolism in vitro. J Agric Food Chem. 2008 Oct 8;56(19):8885-90.b
- Piacente S, Montoro P, Oleszek W, Pizza C., Yucca schidigera bark: phenolic constituents and antioxidant activity. J Nat Prod. 2004 May;67(5):882-5
- Olas B, Wachowicz B, Stochmal A, Oleszek W. Inhibition of oxidative stress in blood platelets by different phenolics from Yucca schidigera Roezl. bark., Nutrition. 2003 Jul-Aug;19(7-8):633-40.
- Cheeke PR, Piacente S, Oleszek W., Anti-inflammatory and anti-arthritic effects of Yucca schidigera: a review. J Inflamm (Lond). 2006 Mar 29;3:6.
Milk Thistle Many standard treatments for gout involve medications that can be toxic to the liver. Healthy liver functioning is important for the treatment of gout. Silymarin or Silybum marianum from the herb milk thistle supports the wellbeing of the liver.
- Rakel: Integrative Medicine, 2nd ed. 2007 Saunders. Chapter 84.
Turmeric Root (curcuma longa) Turmeric may exert some anti-inflammatory properties by inhibiting chemicals called prostaglandins. These chemicals promote inflammation and pain in a gout attack.
- Rakel: Integrative Medicine, 2nd ed. 2007 Saunders. Chapter 48.
Dandelion Extract The dandelion, thought of as a weed by so many, has been used for centuries in traditional herbal medicines. It is accepted by the German Commission E to use for "biliary abnormalities, appetite loss, dyspepsia, and for stimulation of diuresis." Dandelion leaves contain a number of different active constituents, including quercetin, luteolin and inulin which help maintain a healthy liver. In gout, dandelion extract is most useful for its anti-inflammatory and antioxidant properties as well as for its abilities to stimulate the urinary excretion of uric acid, thought to be the cause of gout pain.
- Williams CA, Goldstone F, Greenham J. Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry 1996;42:121-7.
- Mascolo N, Autore G, Capassa G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987:28-9.
- Racz-Kotilla E, Racz G, Solomon A. The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med 1974;26:212-7.
- Schutz, K., Carle, R., and Schieber, A. Taraxacum--a review on its phytochemical and pharmacological profile. J Ethnopharmacol 10-11-2006;107(3):313-323.
- Grases, F., Melero, G., Costa-Bauza, A., Prieto, R., and March, J. G. Urolithiasis and phytotherapy. Int Urol Nephrol. 1994;26(5):507-511
- Hu, C. and Kitts, D. D. Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells. Mol.Cell Biochem 2004;265(1-2):107-113.
Rutin leaf extract has some effect on inhibit the enzyme responsible for making gout crystals (i.e. XO or xanthine oxidase generates uric acid), and preventing the formation of crystals from uric acid. This extract also has anti-inflammatory properties. 31
- Pharmacological basis for use of Pistacia integerrima leaves in hyperuricemia and gout. Ahmad NS, Farman M, Najmi MH, Mian KB, Hasan A. J Ethnopharmacol. 2008 May 22;117(3):478-82.
- Effects of Biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver. Zhu JX, Wang Y, Kong LD, Yang C, Zhang X. J Ethnopharmacol. 2004 Jul;93(1):133-40.
